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DeCS
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Descriptor English:
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Cyclic Nucleotide Phosphodiesterases, Type 3
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Descriptor Spanish:
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fosfodiesterasas de nucleótidos cíclicos tipo 3
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Descriptor Portuguese:
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Nucleotídeo Cíclico Fosfodiesterase do Tipo 3
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Synonyms English:
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Cyclic Nucleotide Phosphodiesterase PDE3 Family
Cyclic Nucleotide Phosphodiesterases, Type 3A
Cyclic Nucleotide Phosphodiesterases, Type 3B
Phosphodiesterase 3A
Phosphodiesterase 3B
Phosphodiesterase III
Phosphodiesterase, cGMP-Inhibited
cGMP Inhibited Cyclic Nucleotide Phosphodiesterase
cGMP Inhibited Phosphodiesterase
cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase
cGMP-Inhibited Phosphodiesterase
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Tree Number:
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D08.811.277.352.640.150.300
D12.644.360.008.300
D12.776.476.008.300
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Definition English:
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A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing. |
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Entry Combination - descr/qualif English:
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Cyclic Nucleotide Phosphodiesterases, Type 3/antagonists & inhibitors use Phosphodiesterase 3 Inhibitors
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History Note English:
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2008(1995)
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Allowable Qualifiers English:
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Record Number:
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52678
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Unique Identifier:
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D054684
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Occurrence in VHL:
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Similar:
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DeCS
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